Figure 3
Microbiome alpha- and beta-diversity as a function of APOE. Alpha-diversity is depicted as boxplots (A,B,D,E) and beta-diversity as PCoA plots (C,F). These results are from male mice at 3-months of age. Statistical significance for the findings is indicated below each graph. Ellipses in C and F represent 95% confidence intervals. Dominant model (C) R2 = 0.171 and co-dominant model (F) R2 = 0.206. Beta-diversity was also analyzed using a PERMDISP, which had no significant p-values, indicating that variances were not significantly different as a function of APOE.
