Figure 4

Heatmaps depict overall microbiota profiles grouped by APOE status. These heatmaps depict per-sample relative abundance for family-level bacteria in female and male mice. Columns were grouped by APOE status, rows were grouped by the Ward clustering algorithm using Pearson Correlation Coefficient distance measures. Colored boxes highlight groups of taxa that follow either an APOE2- (A.2 and B.2), APOE3- (A.3 and B.3) or APOE4-associated pattern (A.4 and B.4).