Figure 6

The phylogenetic branch defined by Erysipelotrichia and its lower taxa shows a significant association with APOE in male mice. All depicted bacteria were significantly associated with APOE status. The relative abundance of these bacteria increased in a stepwise fashion from APOE2 to APOE3 to APOE4. P values have been corrected using an FDR approach. (A–C) Are the plots depicted using the dominant model representation, while (D–F) are the plots depicted using the co-dominant model representation. These results are derived from 3-month male mice.