Table 2 Microbiome beta-diversity significantly associated with APOE status in male, but not female, mice.

From: APOE genetics influence murine gut microbiome

Beta-diversity (PERMANOVA)

Taxanomic level

3 month

Males -dominant

Males co-dominant

Feature

p-value

 < 0.002

 < 0.004

R2

0.14

0.20

Genus

p-value

 < 0.001

 < 0.008

R2

0.15

0.18

Family

p-value

 < 0.004

 < 0.013

R2

0.17

0.21

Order

p-value

 < 0.004

 < 0.015

R2

0.21

0.24

Class

p-value

 < 0.004

 < 0.015

R2

0.21

0.24

Phylum

p-value

 < 0.035

 < 0.112

R2

0.12

0.15

  1. The R2 values represent the proportion of the variance captured by APOE alleles. The PERMANOVA results were derived from 999 permutations. Values for 5- and 7-month male mice and female mice are contained within Tables S3 and S4.
  2. Significance p-values are in bold font.
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