Figure 2 | Scientific Reports

Figure 2

From: Induction of CD73 prevents death after emergency open aortic surgery for a ruptured abdominal aortic aneurysm: a randomized, double-blind, placebo-controlled study

Figure 2

Individual CD73 responses (A) in the active vs. placebo arms (no significant difference), (B) in patients that survived vs. patients that died by D30 (i.e. all study patients), mean max CD73 achieved between groups 6.09 ng/mL (SD, 4.95 ng/mL) correspondingly for patient without glucocorticoids vs. 2.37 ng/mL (SD, 0.90 ng/mL) (Satterthwaite t-test, P < 0.001), and (C) in patients that received vs. did not receive overlapping glucocorticoids with IV IFN beta-1a (i.e. active arm only), mean max CD73 achieved between groups 6.52 ng/mL (SD, 5.37 ng/mL) for patient without glucocorticoids vs. with glucocorticoids 2.37 ng/mL (SD, 0.91 ng/mL) (Satterthwaite t-test, P = 0.0026).

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