Table 2 Correlation between clinicopathologic findings and DKK1 & β catenin level according CD8 expression.

From: Prognostic value of Dickkopf-1 and ß-catenin expression according to the antitumor immunity of CD8-positive tumor-infiltrating lymphocytes in biliary tract cancer

Clinico pathologic feature

CD8 Low expression

CD8 High expression

CD8 Low expression

CD8 High expression

DKK1 Low

DKK1 High

DKK1 Low

DKK1 High

β catenin off

β catenin on

β catenin off

β catenin on

pT stage

  ≤ T2

16

2

31

3

13

5

26

8

  ≥ T3

33

21

28

11

43

11

23

16

 p value

 

0.029

 

0.036

 

0.513

 

0.112

 pN stage

 N0

39

19

49

10

46

12

39

20

  ≥ N1

10

4

10

4

10

4

10

4

 p value

 

0.763

 

0.321

 

0.524

 

0.703

pTNM stage

  ≤ II

21

6

40

6

21

6

32

14

   ≥ III

28

17

19

8

35

10

17

10

  p value

 

0.171

 

0.082

 

1.000

 

0.562

Histologic grade

  Well

17

6

29

2

19

4

25

6

  Mod/poor/un

32

17

30

12

37

12

24

18

 p value

 

0.465

 

0.018

 

0.499

 

0.035

  1. DKK1 Dickkopf relatd protein1, pT stage pathologic T stage, pN stage pathologic N stage.
  2. Histologic grade, mod/poor/un, moderate differentiated/ poorly differentiated/ undifferentiated.
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