Table 2 Discrimination power of other inflammatory and thromboinflammatory markers for severe outcome and comparison with galectin-3.

From: Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients

Biomarker

AUC

95% CI

p value

p value (comparison with galectin-3 AUC)

Galectin-3

0.75

(0.67–0.84)

< 0.0001

–

CRP

0.76

(0.68–0.85)

< 0.0001

0.70

Albumin

0.73

(0.65–0.82)

< 0.0001

0.93

NLR

0.71

(0.62–0.79)

< 0.0001

0.52

Neutrophil count

0.70

(0.61–0.78)

< 0.0001

0.43

Ferritin

0.66

(0.57–0.76)

< 0.01

0.19

Lymphocyte count

0.58

(0.49–0.68)

0.09

0.02

Platelets

0.48

(0.38–0.58)

0.66

< 0.01

D-Dimer

0.69

(0.60–0.79)

< 0.001

0.49

Fibrinogen

0.66

(0.57–0.75)

< 0.01

0.16

INR

0.61

(0.51–0.71)

0.04

0.05

Triglycerides

0.64

(0.54–0.74)

0.01

0.12

AST

0.68

(0.59–0.76)

< 0.001

0.27

  1. ROC curves were performed to determine the discrimination power of each biomarker for severe outcome. The AUC obtained was compared against that of galectin-3 using DeLong’s test for correlated ROC curves. Bold values represent p < 0.05.
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