Figure 7
From: Complement C5aR/LPS-induced BDNF and NGF modulation in human dental pulp stem cells
Effect of C5aR or LPS on cell proliferation of DPSCs and BM-MSCs. Cultured DPSCs (A–F) and MSCs (G–L) under a light microscope. Groups: Resting (A,G), C5aR agonist (B,H), C5aR antagonist (C,I), LPS (D,J), LPS + C5aR agonist (E,K), LPS + C5aR antagonist (F,L). (M,N) Bar graph showing statistical analysis—number of cells normalized as cell proliferation. Generally, C5aR modulation and LPS treatment do not affect DPSCs and BM-MSCs proliferation. Note: a slight increase in cell proliferation was observed in DPSCs stimulated with LPS + C5aR-agonist. Scale bar: 100 µm. *p < 0.05 versus untreated control of resting cells (n = 5).
