Table 2 Symptoms and signs at presentation.

From: Prognosis of COVID-19 pneumonia can be early predicted combining Age-adjusted Charlson Comorbidity Index, CRB score and baseline oxygen saturation

Variables

Disease severity

Vital status at discharge

Moderate

Severe

p-value

Alive

Dead

p-value

n: 288

n: 104

n: 340

n: 52

Days from symptoms onset to Hospital admission, median (IQR)

7 (4–10)

6 (3–8.2)

0.002

7 (4–10)

5 (3–7.2)

0.013

Symptoms and signs

Asymptomatic (n: 385)

12 (92%)

1 (8%)

0.135

13 (100%)

0 (0%)

0.152

Fever (n: 381)

231 (76%)

73 (24%)

0.290

265 (87%)

39 (13%)

0.735

Cough (n: 375)

216 (77%)

66 (23%)

0.196

252 (89%)

30 (11%)

0.029

Dyspnea (n: 380)

129 (66%)

66 (34%)

 < 0.001

161 (83%)

34 (17%)

0.018

Tachypnea (n: 375)

16 (33%)

33 (67%)

 < 0.001

32 (65%)

17 (35%)

 < 0.001

Asthenia (n: 338)

132 (71%)

54 (29%)

0.212

159 (85%)

27 (15%)

0.591

Myalgias (n: 322)

126 (78%)

36 (22%)

0.273

143 (88%)

19 (12%)

0.832

Odynophagia (n: 274)

31 (94%)

2 (6%)

0.008

32 (97%)

1 (3%)

0.109

Diarrhoea (n: 337)

58 (79%)

15 (21%)

0.199

68 (93%)

5 (7%)

0.075

Anosmia (n: 211)

13 (100%)

0 (0%)

0.027

13 (100%)

0 (0%)

0.116

Dysgeusia (n: 208)

12 (92%)

1 (8%)

0.099

13 (100%)

0 (0%)

0.112

Thromboembolism (n: 379)

2 (14%)

12 (86%)

 < 0.001

10 (71%)

4 (29%)

0.091

Haemoptysis (n: 380)

0 (0%)

4 (100%)

 < 0.001

1 (25%)

3 (75%)

 < 0.001

Heart failure (n: 379)

3 (13%)

20 (87%)

 < 0.001

6 (26%)

17 (74%)

 < 0.001

Baseline SpO2 < 90 (n: 392)

19 (28%)

50 (72%)

 < 0.001

38 (55%)

31 (45%)

 < 0.001

Glasgow coma score < 15 (n: 364)

5 (26%)

14 (74%)

 < 0.001

7 (37%)

12 (63%)

 < 0.001

Arterial hypotension (n: 362)

4 (33%)

8 (67%)

 < 0.001

7 (58%)

5 (42%)

 < 0.001

CRB scorea (n: 392)

0

264 (81%)

60 (19%)

 < 0.001

298 (92%)

26 (8%)

 < 0.001

1

23 (40%)

35 (60%)

38 (66%)

20 (34%)

2

1 (13%)

7 (88%)

4 (50%)

4 (50%)

3

0 (0%)

2 (100%)

0 (0%)

2 (100%)

  1. According to the development of severe disease and vital status at discharge.
  2. IQR: interquartile range. SpO2: arterial saturation by pulse oximetry. In each outcome, absolute frequency, percentage by outcome and p-values for the comparation of moderate vs severe disease and alive vs dead at discharge are shown.
  3. aIn the CRB score the vast majority of the patients had a score of zero (83%), which makes the quartiles and range very uninformative, so for a better description in the bivariate analysis we show the absolute and relative frequencies of all values (0–3); its p-value compares 0 points versus more than 0. In each variable, total number of valid data is specified in the first column. In bold and italic those associations that are statistically significant.
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