Table 1 Demographic, clinical characteristics and outcomes of transplant recipients according to the degree of IAH.
From: Impact of intra-abdominal pressure on early kidney transplant outcomes
All patients | No IAH | Grade I IAH | Grade II/III IAH | |
|---|---|---|---|---|
N | 205 | 45 | 117 | 43 |
Age, years1 | 61 (51–69) | 61 (48–69) | 62 (52–70) | 61 (53–68) |
Male sex, n (%) | 133 (64.9) | 20 (44.4) | 77 (65.8) | 36 (83.7) |
Caucasians, n (%) | 202 (98.5) | 45 (100) | 116 (99.1) | 41 (95.3) |
Months on dialysis, months1 | 18 (10–33) | 13 (7–37) | 17 (9–31) | 29 (13–43) |
BMI, kg/m2 2 | 25.9 ± 3.9 | 23.6 ± 3.4 | 26 ± 3.7 | 27.9 ± 3.6 |
Polycystic kidney disease, n (%) | 40 (19.5) | 7 (15.6) | 27 (23.1) | 6 (14) |
Peritoneal dialysis as RRT, n (%) | 83 (40.5) | 25 (55.6) | 45 (38.5) | 13 (30.2) |
First renal transplant, n (%) | 173 (84.4) | 35 (77.8) | 104 (88.9) | 34 (79.1) |
Hypertension, n (%) | 181 (88.3) | 36 (80) | 107 (91.5) | 38 (88.4) |
Diabetes, n (%) | 34 (16.6) | 3 (6.7) | 21 (17.9) | 10 (23.3) |
Age (donor), years1 | 60 (50–72) | 56 (46–64) | 62 (51–72) | 60 (50–72) |
Male sex (donor), n (%) | 134 (65.4) | 29 (64.4) | 75 (64.1) | 30 (69.8) |
Donation after cardiac death, n (%) | 16 (7.8) | 4 (8.9) | 8 (6.8) | 4 (9.3) |
Donor KDPI, percentage points1 | 75 (53–96) | 63 (43–88) | 78 (56–96) | 78 (52–96) |
Surgery duration, min1 | 185 (170–214) | 173 (160–209) | 190 (170–215) | 193 (175–220) |
Cold ischemia time, hours1 | 16 (13–19) | 17 (14–19) | 17 (13–19) | 16 (13–18) |
HLA mismatches, number1 | 4 (4–5) | 5 (4–6) | 4 (4–5) | 4 (3–5) |
Day 0 mean IAP, mmHg1 | 12 (9.7–14) | 8.3 (7–10.2) | 12 (10.5–13) | 16.3 (15–18) |
Day 1 mean IAP, mmHg1 | 12.3 (9.7–14) | 9 (8–10) | 12.7 (11–13.4) | 15.8 (14–17) |
Day 2 mean IAP, mmHg1 | 12.5 (10–14) | 9.5 (8.4–10.7) | 12.7 (11–13.7) | 15.8 (13.7–17.3) |
72 h mean IAP, mmHg1 | 12.1 (10.4–13.9) | 9.1 (8.1–9.9) | 12.1 (11.1–13) | 15.6 (14.6–16.8) |
72 h mean MAP, mmHg1 | 93.9 (90.8–97.6) | 93.8 (90.6–96.7) | 94.2 (91.1–98.1) | 92.7 (90–97) |
72 h accumulated fluid balance, L1 | 3.9 (2.6–5.1) | 3.9 (2.6–4.9) | 3.9 (2.4–5.1) | 3.9 (2–5.6) |
Outcomes | ||||
Renal resistive index1 | 0.76 (0.7–0.83) | 0.77 (0.7–0.82) | 0.75 (0.7–0.8) | 0.8 (0.73–0.88) |
Graft failure or death at discharge, n (%) | 13 (6.3) | 1 (2.2) | 6 (5.1) | 6 (14) |
Delayed graft function, n (%) | 54 (26.3) | 5 (11.4) | 26 (22.6) | 23 (54.8) |
Postoperative complications, n (%) | 86 (42) | 20 (44.4) | 41 (35) | 25 (58.1) |
SCr at discharge, mg/dL1 | 2 (1.51–3.19) | 1.68 (1.33–2.22) | 2.09 (1.51–3.03) | 2.94 (1.8–4.62) |
SCr at 3 months, mg/dL1 | 1.66 (1.31–2.14) | 1.47 (1.16–1.78) | 1.69 (1.33–2.2) | 1.77 (1.42–2.65) |
SCr at 6 months, mg/dL1 | 1.59 (1.29–2.01) | 1.5 (1.17–1.69) | 1.63 (1.29–2.1) | 1.69 (1.44–2.05) |
Days until SCr < 2.0 mg/dL1 | 17 (4–41) | 8 (3–19) | 17 (4–49) | 25 (19–180) |
Biopsy-proven Acute Rejection, n (%) | 6 (2.9) | 2 (4.5) | 4 (3.5) | 0 (0) |
Length of stay, days1 | 14 (12–18) | 13 (11.5–17.5) | 14 (12–17) | 16 (12–22) |
