Figure 2

Findings for THEG. (A) expression of THEG from dataset GSE45885, (B) expression of THEG from dataset GSE45887, (C) expression of THEG from dataset145467, (D) expression of THEG from dataset 9210. The gene expression level of THEG was significantly reduced in patients with Sertoli-cell only syndrome (SCOS) in datasets GSE45885 and GSE45887 when compared to their respective controls. While the expression of THEG is significantly increased in OA group when compared to NOA (GSE9210). Since SCOS is one of the causes of NOA, then THEG expression was significantly reduced in NOA patients from GSE9210 dataset. NOA = non-obstructive azoospermia, OA = obstructive azoospermia, NOA-pre = NOA pre-meiotic arrest, NOA-mei = NOA meiotic arrest, NOA-post = NOA post-meiotic arrest.