Table 1 Description of the 25 single-cell datasets used to assess the performance of imputation methods. The first three columns describe the name, accession ID, and tissue, while the following seven columns show the sequencing protocol, cell isolation technique, quantification scheme, normalized unit, dropout rate, number of cell types, and number of cells.

From: A novel method for single-cell data imputation using subspace regression

Dataset	Accession ID	Tissue	Sequencing protocol	Cell isolation	Quant. scheme	Norm. unit	Drop. rate	Class	Size
1. Fan²⁹	GSE53386	Mouse Embryo	SUPeR-seq	Plate	Reads	FPKM	0.584	6	69
2. Treutlein³⁰	GSE52583	Mouse Tissues	SMARTer	Plate	Reads	FPKM	0.902	5	80
3. Yan³¹	GSE36552	Human Embryo	Tang	Plate	Reads	RPKM	0.456	6	90
4. Goolam³²	E-MTAB-3321	Mouse Embryo	Smart-Seq2	Plate	Reads	CPM	0.685	5	124
5. Deng³³	GSE45719	Mouse Embryo	Smart-Seq	Plate	Reads	RPKM	0.605	6	268
6. Pollen³⁴	SRP041736	Human Tissues	SMARTer	Plate	Reads	TPM	0.671	4	301
7. Darmanis³⁵	GSE67835	Human Brain	SMARTer	Plate	Reads	CPM	0.808	9	466
8. Usoskin³⁶	GSE59739	Mouse Brain	STRT-Seq	Plate	Reads	RPM	0.846	3	622
9. Camp³⁷	GSE75140	Human Brain	SMARTer	Plate	Reads	FPKM	0.801	7	734
10. Klein³⁸	GSE65525	Mouse Embryo	inDrop	Droplet	UMI	RPM	0.658	4	2717
11. Romanov³⁹	GSE74672	Human Brain	SMARTer	Plate	UMI	-	0.878	7	2881
12. Segerstolpe⁴⁰	E-MTAB-5061	Human Pancreas	Smart-Seq2	Plate	Reads	RPKM	0.823	15	3514
13. Manno⁴¹	GSE76381	Human Brain	STRT-Seq	Plate	UMI	-	0.86	56	4029
14. Marques⁴²	GSE75330	Mouse Brain	Fluidigm C1	Plate	Reads	FPKM	0.891	13	5053
15. Baron⁴³	GSE84133	Human Pancreas	inDrop	Droplet	UMI	TPM	0.906	14	8569
16. Sanderson⁴⁴	SCP916	Mouse Tissues	10X Genomics	Droplet	Reads	-	0.764	11	12,648
17. Slyper	SCP345	Human Blood	10X Genomics	Droplet	UMI	-	0.956	8	13,316
18. Zilionis (Mouse)⁴⁵	GSE127465	Mouse Lung	inDrop	Droplet	UMI	RPM	0.976	7	15,939
19. Tasic⁴⁶	GSE115746	Mouse Visual Cortex	SMART-Seq	Plate	Reads	CPM	0.798	6	23,178
20. Zyl (Human)⁴⁷	SCP780	Human Eye	inDrop	Droplet	UMI	-	0.913	19	24,023
21. Zilionis (Human)⁴⁵	GSE127465	Human Lung	inDrop	Droplet	UMI	RPM	0.982	9	34,558
22. Wei⁴⁸	SCP469	Human Synovium	10x Genomics	Droplet	UMI	TPM	0.915	9	41,565
23. Cao⁴⁹	SCP454	Sea Squirt Embryos	10x Genomics	Droplet	UMI	-	0.821	7	90,579
24. Orozco⁵⁰	GSE135133	Human Eye	10X Genomics	Droplet	UMI	RPKM	0.964	12	100,055
25. Darrah⁵¹	GSE139598	Human Blood	Drop-seq	Droplet	UMI	-	0.947	14	162,490

\(^{1}\) UMI: Unique Molecular Identifier; CPM: Counts Per Million; RPM: Reads Per Million; RPKM: Reads Per Kilobase of transcript, per Million mapped reads; FPKM: Fragments Per Kilobase of transcript, per Million mapped reads.

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