Figure 2
From: Effect of substrate stiffness on friction in collective cell migration
Effect of substrate stiffness and time in culture on RMS velocity and velocity correlation length. (a) Representative color maps of speed of cells on substrates of moduli 6, 18, and 27 kPa at t = 45 h after the cells reached confluence. (b) Autocorrelation of cell velocity C(r) plotted as a function of separation distance r at t = 45 h for a representative cell layer on each substrate stiffness. (c) Velocity correlation length plotted against RMS velocity. The brightness indicates time after confluence and the color family indicates substrate stiffness as indicated in the legend. Each data point represents the average of at least 6 statistically independent samples on each substrate stiffness. (d) Velocity correlation length for each substrate stiffness. Data shown represent averages over time points collected in the range t = 42–48 h after confluence. Each dot represents an independent measurement; horizontal lines indicate means.
