Figure 5 | Scientific Reports

Figure 5

From: A functional screen with metformin identifies microRNAs that regulate metabolism in colorectal cancer cells

Figure 5

Integrated energy maps of HCT116 cells associated with miRNA mimic transfections in combination with metformin treatment. CRC cells were reverse transfected with selected miRNA mimics and treated with 2.5 mM metformin treatment or control medium. The baseline oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) calculated were combined to generate the basal phenogram. The OCR and ECAR values were normalized to viability of the corresponding cells acquired by crystal violet assay. Results are expressed as mean ± SD of 3 technical replicates.

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