Table 3 Associations of retinal layers with occipital and hippocampal volumetric parameters (n = 2872).

	Occipital grey matter volume			Occipital white matter volume			Total hippocampal volume
	Difference (%) [95% CI] per mm³/µm	Difference (%) per SD [95% CI]	p	Difference (%) [95% CI] per mm³/µm	Difference (%) per SD [95% CI]	p	Difference (%) per mm³/µm [95% CI]	Difference (%) per SD [95% CI]	p
mRNFL	2.41 [-0.50; 5.31]	0.29 [-0.06; 0.64]	0.10	5.93 [2.53; 9.35]	0.72 [0.31; 1.14]	< 0.001	2.64 [0.14; 5.13]	0.32 [0.02; 0.62]	0.04
mGCL	12.47 [8.74; 16.20]	1.24 [0.87; 1.62]	< 0.001	15.00 [10.61; 19.39]	1.50 [1.06; 1.93]	< 0.001	13.27 [10.08; 16.47]	1.32 [1.01; 1.64]	< 0.001
mIPL	13.77 [8.86; 18.68]	1.02 [0.66; 1.38]	< 0.001	15.18 [9.40; 20.97]	1.13 [0.70; 1.55]	< 0.001	17.46 [13.26; 21.65]	1.29 [0.98; 1.60]	< 0.001
mINL	-1.95 [-7.53; 3.63]	-0.13 [-0.49; 0.24]	0.49	2.35 [-5.50; 8.91]	0.15 [-0.27; 0.58]	0.43	6.94 [2.16; 11.73]	0.45 [0.14; 0.76]	0.004
mOPL	-0.32 [-5.10; 4.45]	-0.02 [-0.37; 0.32]	0.89	0.11 [-7.34; 5.73]	0.00 [-0.01; 0.01]	0.97	5.78 [1.68; 9.88]	0.42 [0.12; 0.71]	0.005
mONL	1.74 [-0.12; 3.61]	0.33 [-0.02; 0.69]	0.07	-0.10 [-2.30; 2.09]	-0.02 [-0.04; 0.04]	0.93	-0.25 [-1.86; 1.35]	-0.05 [-0.35; 0.26]	0.76
mRPE	4.51 [-5.29; 14.29]	0.16 [-0.19; 0.50]	0.37	3.68 [-7.83; 15.18]	0.13 [-0.28; 0.54]	0.53	11.14 [2.75; 19.54]	0.39 [0.10; 0.69]	0.009
pRNFL	0.14 [0.11; 0.17]	1.49 [1.13; 1.84]	< 0.001	0.19 [0.15; 0.22]	2.00 [1.59; 2.41]	< 0.001	0.10 [0.07; 0.13]	1.06 [0.76; 1.39]	< 0.001
BMO–MRW	0.01 [0.00; 0.01]	0.56 [0.21; 0.92]	0.02	0.02 [0.01; 0.02]	0.96 [0.54; 1.38]	< 0.001	0.01 [0.00; 0.01]	0.48 [0.17; 0.78]	0.002

mRNFL macular retinal nerve fiber layer, mGCL macular ganglion cell layer, mIPL macular inner plexiform layer, mINL macular inner nuclear layer, mOPL macular outer plexiform layer, mONL macular outer nuclear layer, mRPE macular retinal pigment epithelium, pRNFL peripapillary RNFL, BMO–MRW Bruch’s membrane opening–minimum rim width.
Macular layer volumes per mm³; pRNFL and BMO–MRW per µm.

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