Figure 1
From: Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice
Effect of sepsis on survival time in mice. Sepsis (CLP) significantly (p < 0.001) reduced the mean survival time in septic mice (19.97 ± 1.04 h; n = 30) in comparison to the sham-operated (SO) mice. All the SO mice (n = 12) survived during the 72 h observation period. The overall difference in survival rate was determined by the Kaplan–Meier test followed by the log-rank test. *p < 0.001 vs. SO.
