Figure 7
From: Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice
Effect of DAPT pre-treatment on high K+ (80 mM) depolarizing solution-induced contraction in aorta of septic mice. Bar diagrams (A–C) showing the comparative maximum contraction elicited by high K+ (80 mM) solution in the aortic rings isolated from sham-operated (SO), sepsis (CLP), DAPT pre-treated sepsis (DAPT + CLP) and DAPT pre-treated SO (DAPT + SO) groups. Data are presented as mean ± SEM; n = 6. Vertical bars represent SEM. Data were analyzed by unpaired student’s ‘t’ test. *p < 0.05 in comparison to SO.
