Table 1 Baseline characteristics.

From: Nosocomial infections in female compared with male patients with decompensated liver cirrhosis

Variable

All patients

Female

Male

P-value

(n = 203, 36.5%)

(n = 353, 63.5%)

Age (years)

56.8 (11.1)

56.3 (11.4)

57.1 (11.0)

0.448

Etiology of liver cirrhosis

Alcohol-related

52% (n = 291)

44% (n = 89)

57% (n = 202)

0.002

Cryptogenic

11% (n = 61)

13% (n = 27)

10% (n = 34)

0.183

Viral

18% (n = 102)

17.2% (n = 35)

19% (n = 67)

0.61

NASH

7% (n = 38)

7% (n = 15)

7% (n = 23)

0.694

Cholestatic

8% (n = 42)

11% (n = 23)

5% (n = 19)

0.011

Other

14% (n = 79)

16% (n = 33)

13% (n = 46)

0.294

Mixed

10% (n = 55)

9% (n = 19)

10% (n = 36)

0.75

Cause of hospitalization

Ascites

65% (n = 361)

65% (n = 131)

65% (n = 230)

0.882

TIPS-Evaluation

20% (n = 110)

16% (n = 33)

22% (n = 77)

0.113

LTx-Evaluation

14%(n = 78)

14% (n = 29)

14% (n = 49)

0.895

HE

6% (n = 32)

5% (n = 10)

6% (n = 22)

0.524

HRS

3% (n = 17)

1% (n = 3)

4% (n = 14)

0.101

Worsening of general condition

5% (n = 26)

4% (n = 9)

5% (n = 17)

0.837

Infection

2% (n = 10)

2% (n = 4)

2% (n = 6)

0.817

ACLF

2% (n = 10)

2% (n = 4)

2% (n = 6)

0.817

Other cause

29%(n = 161)

34% (n = 69)

26% (n = 92)

0.047

PPI intake

81% (n = 445)

77% (n = 154)

83% (n = 291)

0.078

Β-blockers

38% (n = 212)

34% (n = 69)

41% (n = 143)

0.136

Esophageal varices

76% (n = 422)

69% (n = 140)

80% (n = 282)

0.003

Diabetes

24% (n = 135)

23% (n = 47)

25% (n = 88)

0.638

MELD score

18 (7.0)

17 (6.6)

19 (7.2)

0.016

Albumin (g/l)

27.1 (5.9)

26.6 (5.4)

27.4 (6.2)

0.273

Bilirubin (µmol/l)

91.9 (135.4)

86.6 (130.6)

94.9 (138.2)

0.488

CRP (mg/l)

30.4 (34.7)

30.1 (38.3)

30.5 (32.5)

0.903

INR (Ratio)

1.53 (0.46)

1.49 (0.37)

1.55 (0.50)

0.209

Creatinine (µmol/l)

130.6 (89.2)

115.6 (70.5)

139.2 (97.3)

0.003

Leukocytes (103/µl)

8.8 (6.1)

9.3 (5.9)

8.6 (6.2)

0.164

Platelets (103/µl)

147.6 (102.7)

160 (119.7)

140 (90.8)

0.029

Sodium (mmol/l)

134 (5.4)

134 (5.5)

134 (5.3)

0.863

Antibiotic intake within 12 weeks before admission

33% (n = 180)

32% (n = 64)

33% (n = 116)

0.818

  1. All continues variables are displayed as mean with standard deviation. Categorical variables are displayed as proportions.
  2. Laboratory values were assessed at time of admission.
  3. In some patients several causes of hospitalization were present.
  4. Significant values are in bold.
  5. MELD model of end stage liver disease, HE hepatic encephalopathy, HRS hepatorenal syndrome, TIPS transjugular intrahepatic portosystemic shunt, LTx liver transplantation, ACLF acute on chronic liver failure, PPI proton pump inhibitors, CRP C-reactive protein, INR international normalized Ratio.