Table 1 IC50 values of the synthesized compounds and acarbose regarding α-amylase and α-glycosidase inhibitory activities.

From: Antidiabetic, antioxidant, and anti-obesity effects of phenylthio-ethyl benzoate derivatives, and molecular docking study regarding α-amylase enzyme

Compounds

α-Amylase enzyme IC50 (µg/ml), ± SD

α-Glycosidase enzyme IC50 (µg/ml), ± SD

2a

3.57 ± 1.08

10.09 ± 0.70

2b

12.44 ± 0.82

89.95 ± 0.49

2c

19.55 ± 0.96

78.1 ± 0.76

2d

13.41 ± 0.76

114.17 ± 1.04

Acarbose

6.47 ± 1.01

44.79 ± 0.33

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