Table 3 Pooled estimates for prognostic accuracy of MRI with abnormal lesions for DNS diagnosis by subgroup.

Sample size

≥ 100

5

0.710 (0.644–0.769)

0.851 (0.825–0.875)

4.302 (2.861–6.470)

0.364 (0.284–0.467)

11.917 (6.201–22.904)

0.880 (0.117)

0.710 (0.099)

< 100

3

0.700 (0.506–0.853)

0.824 (0.758–0.878)

3.901 (2.614–5.821)

0.375 (0.217–0.647)

10.845 (4.489–26.200)

0.849 (0.078)

0.780 (0.073)

Inclusion criteria

Any level of COHb

5

0.672 (0.579–0.757)

0.823 (0.788–0.855)

3.706 (2.668–5.146)

0.413 (0.318–0.537)

9.245 (5.319–16.067)

0.781 (0.103)

0.720 (0.088)

Clinical sign and symptom

3

0.744 (0.656–0.819)

0.884 (0.848–0.913)

5.526 (3.410–8.954)

0.293 (0.216–0.397)

22.980 (13.555–38.653)

0.864 (0.098)

0.795 (0.096)

Timing of imaging examination

≤ 72 h

4

0.706 (0.627–0.777)

0.852 (0.822-.879)

4.195 (2.290–7.684)

0.391 (0.064–0.578)

10.797 (3.973–29.344)

0.756 (0.175)

0.698 (0.146)

Unclear

4

0.714 (0.605–0.808)

0.843 (0.797–0.882)

4.496 (3.312–6.102)

0.340 (0.242–0.478)

13.999 (7.791–25.155)

0.853 (0.076)

0.784 (0.072)

Hyperbaric oxygen therapy

≥ 80%

5

0.710 (0.633–0.778)

0.849 (0.819–0.875)

4.145 (2.507–6.852)

0.379 (0.269–0.534)

11.263 (4.785–26.512)

0.810 (0.099)

0.745 (0.087)

< 80%

3

0.707 (0.590–0.806)

0.849 (0.800–0.891)

4.646 (3.312–6.516)

0.346 (0.243–0.493)

13.999 (7.517–26.072)

0.843 (0.141)

0.774 (0.131)

Quality of study

High quality

6

0.706 (0.641–0.766)

0.855 (0.826–0.878)

4.437 (2.954–6.664)

0.369 (0.288–0.474)

12.023 (6.301–22.940)

0.773 (0.133)

0.713 (0.112)

Low quality

2

0.737 (0.488–0.909)

0.802 (0.711–0.875)

3.705 (2.293–5.985)

0.334 (0.157–0.711)

11.202 (3.596–34.892)

–

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