Table 1 Baseline characteristics of the 25 participants.
N | Mean (SD) or frequency (%) | |
---|---|---|
Age—years | 25 | 12.3 (3.5) |
Female sex | 16 | 64% |
White race | 24 | 96% |
Non-Hispanic ethnicity | 20 | 80% |
Sibling age at T1D diagnosis—years | 25 | 7.4 (3.8) |
Number of first-degree relatives with T1D | ||
1 | 22 | 88% |
≥ 2 | 3 | 12% |
BMI Z-score | 25 | 0.43 (1.09) |
Pubertal stageA | ||
Pre-pubertal | 10 | 40% |
Early/mid-pubertal | 5 | 20% |
Late/post-pubertal | 10 | 40% |
HLA genotype | ||
Non-DR3 and non-DR4 | 15 | 60% |
DR3 and/or DR4 | 10 | 40% |
Number of positive autoantibodies | ||
0 | 19 | 76% |
1 | 2 | 8% |
≥ 2 | 4 | 16% |
Positive autoantibodies | ||
GAD65 | 6 | 24% |
IA-2 | 2 | 8% |
IAA | 1 | 4% |
ZnT8 | 4 | 16% |