Figure 7
The expression of multiple DMD gene products are significantly associated with LGG survival outcomes. (a) LGG TCGA RNAseq data for each DMD isoform was dichotomised into high (blue) and low (red) expression groups and survival analysis performed in GraphPad using the log-rank test. Numbers in brackets are median overall survival times in months. (b) Kaplan–Meier survival curves for high (blue) vs low (red) Dp71, Dp71ab or Dp427m expression for each IDH mutation status group were compared. Numbers in brackets are median overall survival times in months. The tables provide the log-rank test P values for each planned comparison; the alpha value was adjusted to 0.017 to correct for multiple testing.
