Figure 8
Exploratory analysis of the DEGs in LGG cases with high versus low Dp71, Dp71ab and Dp427m expression. (a) Venn analysis of the DEGs identified from high vs low overall DMD, Dp71, Dp71ab and Dp427m expression. The five DEGs common to all are listed. (b) STRING PPI networks of DEGs. Edge thickness indicates confidence, disconnected nodes are hidden. (c) Network tree visualisation of the enriched pathways in DEGs using the GO biological processes gene annotation, dot size corresponds to adjusted P values. Note no significant enrichment was found for Dp71 DEGs. (d) Pathway analysis using GO biological processes gene annotation. The heatmap was produced in GraphPad and displays the top 10 GO terms for high vs low DMD, Dp71, Dp71ab and Dp427m. Upregulated (red) and downregulated (blue) pathways are indicated.
