Figure 6
From: The metabolism of cells regulates their sensitivity to NK cells depending on p53 status

DCA slightly affect cell tumor growth in NSG mice engrafted with lymphoma cells. (A) Five NSG mice/group were subcutaneously engrafted with 5 × 106 BCLP2 and treated with DCA, with e-NK and/or with an anti-CD20 mAb. Graphs show tumor cell growth. (B) Mice survival after different treatments. (C) Five NSG mice/group were subcutaneously engrafted with 10 × 106 LNH1 (right) cells and treated with metformin and/or with e-NK. Graphs show tumor cell growth. (D) Tumor cell growth at day 31 after LNH1 engraftment. Graphs show means ± SD, ***p < 0.005; 2 way Anova compared to non-treated cells.