Figure 3

OCT and ERG measurements using an Integrated OCT-Electrophysiology system. (A) B-scan OCT image of wild type pig retina illustrates distinct layers. (B) Enface image of wild type pig retina reconstructed from C-scan OCT imaging. (C) A representative full-field scotopic ERG of wild type pig. (D) B-scan OCT image of transgenic P23H pig retina shows loss of ONL. (E) Enface image of transgenic P23H pig retina reconstructed from C-scan OCT imaging. (F) A representative full-field scotopic ERG of transgenic P23H pig. GCL ganglion cell layer, IPL inner plexiform layer, INL inner nuclear layer, OPL outer plexiform layer, ONL outer nuclear layer.