Table 5 Enriched pathways and GO terms in pan-cancer.

From: Computing microRNA-gene interaction networks in pan-cancer using miRDriver

REACTOMEa

KEGGb

GO termsc

Immune System

Metabolism

Signal Transduction

Innate Immune System

Hemostasis

Transport of small molecules

Developmental Biology

Signaling by GPCR

Class A/1 (Rhodopsin-like receptors)

GPCR ligand binding

GPCR downstream signalling

G alpha (i) signalling events

Neuronal System

Neuroactive Ligand Receptor Interaction

Metabolism of Xenobiotics by Cytochrome P450

Steroid Hormone Biosynthesis

Retinol Metabolism

Drug Metabolism Cytochrome P450

Cytokine-Cytokine Receptor Interaction

Systemic Lupus Erythematosus

Receptor ligand activity

Receptor regulator activity

Ion gated channel activity

Gated channel activity

Cation channel activity

Substrate-specific channel activity

Passive transmembrane transporter activity

Extracellular matrix

Ion channel activity

Nucleosome

DNA packaging complex

Nuclear nucleosome

Protein-DNA complex

Hormone activity

  1. The pathways that appeared in more than four cancer types are in bold.
  2. aREACTOME pathways, bKEGG pathways and cGO terms that were found to be enriched in at least two cancer types.