Figure 2

(a) Plated k-wires at day 28 show an infection rate of 100% in group titan and genta. At day 28 examination group titan/syst. resulted in an infection rate of 98.75%. Group genta/syst. resulted with the lowest infection rate with a percentage of 62.5%, which is demonstrated in Fig. 1a. (b) The evaluation of the homogenized tibiae showed a high amount of CFU in the examination group that was only treated with a titanium implant. The amount of CFU was noticeably higher than in the groups genta, expl./syst. and genta/syst. followed by group titan/syst. without significant difference. A low amount of CFU was counted in the groups genta, expl./syst. and genta/syst. (c) Evaluation of homogenized bone occurred with a special focus on the development of SCVs. Results show synthesis of SCVs in 4 animals of group genta, 2 animals of group titan, expl./syst. and titan/syst. and 1 animal of group genta/syst.