Figure 4
(a) Shows representative slices of a tibia of each group colored with Masson–Goldner for histological analysis. Group expl./syst. shows massive signs of bone infection like osteolyses, abscesses and formation of sequestra (arrow). Group titan reveals increase of granulocytes and osteolysis as well genta and titan/syst. and also shows periosteal enlargement. Only group genta/syst. shows few signs of infection with little formation of osteolysis and a non-infected drill channel. (b) Statistical analysis of the development of histological signs of infection of all data demonstrated as boxplots.
