Table 1 Subdivision and group size of all examination groups.

From: Establishment of a reliable in-vivo model of implant-associated infection to investigate innovative treatment options

Examination group

First operation

Second operation (nail exchange = NE)

Analysis

"titan "

Uncoated titanium implant + 

20 μl S. aureus inoculum

Staphylokokkus aureus-Suspension (n = 120)

New uncoated titanium implant (n = 24)

Microbiologic analysis (n = 8)

Immunohistochemical and cytochemical analysis (n = 8)

Histologic analysis (n = 8)

"genta "

Coated implant with a combined coating of PDLLA + 10% gentamicine (n = 24)

Microbiologic analysis (n = 8)

Immunohistochemical and cytochemical analysis (n = 8)

Histologic analysis (n = 8)

“expl./syst.”

Leaving the medullary space without an implant + gentamicin systemically (n = 24)

Microbiologic analysis (n = 8)

Immunohistochemical and cytochemical analysis (n = 8)

Histologic analysis (n = 8)

“titan/syst.”

New uncoated titanium implant + gentamicin systemically (n = 24)

Microbiologic analysis (n = 8)

Immunohistochemical and cytochemical analysis (n = 8)

Histologic analysis (n = 8)

“genta/syst.”

Coated implant with a combined coating of PDLLA + 10% gentamicine + gentamicin systemically (n = 24)

Microbiologic analysis (n = 8)

Immunohistochemical and cytochemical analysis (n = 8)

Histologic analysis (n = 8)