Figure 5 | Scientific Reports

Figure 5

From: Computational identification of new potential transcriptional partners of ERRα in breast cancer cells: specific partners for specific targets

Figure 5

Regulation of gene expression by ERRα and suspected co-regulators. (a, b) MDA-MB-231 cells transfected with siRNAs directed against the indicated transcription factors were analyzed for expression of the indicated genes by RT-qPCR. Results are presented relative to control conditions with bars representing mean + /- sem of three independent experiments performed in triplicate. (a) Validation of siRNA effect on their corresponding direct targets. (b) Analysis of ERRα target gene. As evaluated by t-test, variations are not significant unless indicated by ***p < 0.001, **p < 0.01, *p < 0.05.

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