Table 1 Clinical and metabolic characteristics of 88 Afro-Caribbean adult survivors of severe malnutrition (SOMs) and 84 community participants (CPs).

From: Liver fat in adult survivors of severe acute malnutrition

 

Severe wasting survivors (SWs) (45)

Oedematous malnutrition survivors (OMs) (43)

P-value SWs vs OMs

Survivors of malnutrition (SOMs) (88)

Community participants (CPs) (84)

P-value SOMs v CPs

Age (years)

26.6 ± 8.8

30.7 ± 8.8

0.02

28.7 ± 8.8

28.8 ± 7.9

0.82

% Women

40

51

0.3

45

47

0.83

Birth weight (kg)

2.5 ± 0.8

3.0 ± 0.7

0.007

2.7 ± 0.8

–

–

BMI (kg/m2)

22.3 ± 5.4

25.1 ± 5.3

0.01

23.6 ± 5.5

23.4 ± 4.3

0.82

Waist (cm)

76.0 ± 12.9

81.7 ± 12.3

0.03

78.7 ± 12.8

78.4 ± 11.1

0.85

Fat mass (kg)

8.3 (3.9, 15.7)

16.0 (4.5, 31.0)

0.05

10.5 (4.1, 23.6)

11.2 (4.9, 21.9)

0.93

Lean Mass (kg)

46.6 (38.7, 53.9)

46.9 (40.0, 56.3)

0.21

46.7 (39.8, 54.6)

49.5 (38.2, 58.8)

0.27

% Body fat

16.1 (6.7, 29.2)

25.9 (7.6, 40.9)

0.07

18.1 (7.0, 35.1)

19.8 (7.6, 36.6)

0.94

VAT area (cm2)

27.3 (16.3, 45.0)

36.8 (19.4, 56.1)

0.68

35.3 (18.0, 47.9)

34.4 (16.3, 53.9)

0.66

SAT area (cm2)

66.5 (20.2, 130.0)

121.3 (30.9, 276.6)

0.09

86.4 (24.7, 219.3)

88.9 (22.3, 189.7)

0.41

VAT:SAT ratio

0.5 (0.2, 1.1)

0.3 (0.2, 0.7)

0.46

0.4 (0.2, 0.8)

0.4 (0.3, 0.7)

0.32

Mean Liver Attenuation (Hounsfield units)

63.7 ± 4.4

64.5 ± 4.9

0.45

64.1 ± 4.6

63.0 ± 4.2

0.11

L/S

1.2 (1.1, 1.3)

1.2 (1.2, 1.3)

0.71

1.2 (1.1, 1.3)

1.2 (1.1, 1.2)

0.025

Fasting Glucose (mmol/L)

4.6 ± 0.5

4.6 ± 0.4

0.66

4.6 ± 0.5

4.6 ± 0.5

0.69

Fasting Insulin (µIU/mL)

3.8 (2.5, 5.9)

3.3 (2.2, 5.5)

0.91

3.6 (2.4, 5.7)

3.2 (1.6, 7.5)

0.40

HOMA-IR

0.8 (0.5, 1.1)

0.7 (0.4, 1.1)

0.64

0.7 (0.5, 1.1)

0.7 (0.3, 1.4)

0.35

Total-C (mmol/L)

3.7 ± 0.8

3.8 ± 0.8

0.33

3.8 ± 0.8

4.0 ± 0.8

0.06

HDL-C (mmol/L)

1.3 ± 0.3

1.3 ± 0.3

0.29

1.3 ± 0.3

1.1 ± 0.3

0.0001

LDL-C (mmol/L)

2.1 ± 0.6

2.2 ± 0.7

0.72

2.1 ± 0.7

2.5 ± 0.9

0.0006

Triglyceride (mmol/L)

0.7 ± 0.2

0.8 ± 0.5

0.36

0.7 ± 0.4

0.7 ± 0.3

0.63

ALT (IU/L)

8.0 (6.0, 10.0)

8.0 (6.0, 12.3)

0.97

8.0 (6.0, 11.0)

8.0 (6.0, 10.0)

0.15

  1. Characteristics of the study sample were compared by the independent sample t-test for continuous variables, and Pearson Chi square test for categorical variables. Normally distributed data are presented as means ± SDs and skewed data as medians (quartiles).
  2. VAT visceral adipose tissue, SAT subcutaneous adipose tissue, VAT:SAT ratio VAT/SAT, L/S liver spleen ratio, HOMA-IR homeostatic model assessment of insulin resistance, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine aminotransferase.
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