Table 3 Biochemical markers of bone metabolism and bone mineral density in patients and controls.

From: Bone metabolism in patients with type 1 neurofibromatosis: key role of sun exposure and physical activity

 

Patients

Controls

p

Phenotype

Calcium mg/dl

9.6 ± 0.88

9.9 ± 0.4

0.009

Calcitonin pg/ml

3.4 ± 2.7

9.6 ± 2

p < 0.01

Osteocalcin ng/ml

121 ± 15

67 ± 5

p < 0.01

CTX ng/ml

1.64 ± 0.04

0.42 ± 0.005

p < 0.01

Vitamin D ng/ml

21 ± 7.3

45 ± 15

p < 0.01

z-score

− 1.1 ± 1

0.1 ± 0.9

p < 0.01

Mild

Calcitonin pg/ml

3.5 ± 2

9.2 ± 1.4

p < 0.01

Vitamin D ng/ml

19.5 ± 7

44.3 ± 12

p < 0.01

z-score

− 1 ± 0.8

0.2 ± 0.9

0.02

Moderate

Calcitonin pg/ml

3.15 ± 2.3

9.3 ± 2.1

p < 0.01

Vitamin D ng/ml

25.6 ± 17

47.4 ± 15

p < 0.01

z-score

− 0.9 ± 1.2

0.04 ± 0.9

0.0005

Severe

Calcitonin pg/ml

4.8 ± 3

10 ± 2

p < 0.01

Vitamin D ng/ml

15.2 ± 6

43.9 ± 15

p < 0.01

z-score

− 0.6 ± 1.4

0.16 ± 0.9

0.01

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