Figure 2
From: ACE2 protein expression in lung tissues of severe COVID-19 infection
Landscape of ACE2. Large patches of ACE2 positive staining in control tissue of (A) testis, (B) kidney, and (C) in adrenal. Representative images of (D) control and (E) COVID-19 infected lung sections showing increased ACE2 staining in COVID-19 cases (brown colour, arrows, and insets, D and E). (F) Quantitative analysis of ACE2 IHC intensity in various control tissues. The difference in the mean intensities was calculated using Wilcox test. Significance denoted by exact P values (n = 13 random images from 15 control lung tissue section, n = 11 images from 2 control testis tissue section, n = 9 images from 2 control kidney tissue section, n = 15 images from 2 control adrenal tissue section). (G, H) Quantitative analysis of ACE2 IHC intensity in control and COVID-19 lung section (G) without sampling analysis (n = 45 images from 15 control lung tissue section and n = 175 images from 44 COVID-19 lung tissue section) and (H) with random sampling analysis (n = 45 images in each group). The difference in the mean intensities was calculated using the Wilcox test, and the exact P value denoted significance.
