Table 1 Test–retest analyses.

From: Cold evoked potentials elicited by rapid cooling of the skin in young and elderly healthy individuals

 

Age group

Test I (mean ± sd)

Test II (mean ± sd)

ICC (95% CI)

Bland–Altman coefficients (mean ± 1.96 SD)

N

A. Hand dorsum

N2 latency (ms)

Young

235 ± 28

248 ± 39

0.35 (−0.14 to 0.72)

−12.9 ± 74.3

15

Elderly

260 ± 35

278 ± 71

0.59 (0.03–0.88)

−18.0 ± 98.0

10

N2P2 amplitude (μV)

Young

28.6 ± 9.6

27.8 ± 10.9

0.89 (0.70–0.96)

0.7 ± 9.8

15

Elderly

13.7 ± 6.3

10.7 ± 7.0

0.59 (0.13–0.85)

3.0 ± 11.1

14

Cold Rating (NRS)

Young

2.5 ± 1.1

2.4 ± 1.2

0.85 (0.60–0.95)

0.1 ± 1.2

15

Elderly

2.2 ± 0.9

2.4 ± 1.4

0.62 (0.19–0.85)

−0.2 ± 2.0

16

B. Hand palm

N2 latency (ms)

Young

290 ± 33

289 ± 21

0.29 (−0.34 to 0.72)

1.2 ± 65.2

13

Elderly

331 ± 63

317 ± 73

0.91 (0.65–0.98)

14.4 ± 54.3

9

N2P2 amplitude (μV)

Young

19.4 ± 8.9

16.1 ± 8.0

0.45 (−0.02 to 0.77)

3.3 ± 17.1

15

Elderly

11.5 ± 7.2

10.7 ± 5.0

0.41 (−0.22 to 0.79)

0.8 ± 13.5

12

Cold rating (NRS)

Young

2.5 ± 1.1

2.6 ± 1.1

0.87 (0.65–0.96)

−0.17 ± 1.1

15

Elderly

2.8 ± 1.3

2.8 ± 1.3

0.85 (0.63–0.95)

0.1 ± 1.4

16

C. Foot dorsum

N2 latency [ms]

Young

371 ± 45

357 ± 59

0.53 (−0.05 to 0.85)

13.9 ± 99.9

11

Elderly

452 ± 64

449 ± 71

−0.69 (−1.85 to 0.77)

3.8 ± 225.4

4

N2P2 amplitude [μV]

Young

20.0 ± 10.4

19.6 ± 7.1

0.89 (0.63–0.97)

0.4 ± 8.6

11

Elderly

9.5 ± 4.4

6.5 ± 6.2

0.23 (−0.42 to 0.77)

3.0 ± 12.9

8

Cold Rating (NRS)

Young

2.1 ± 0.8

2.0 ± 1.0

0.71 (0.25–0.91)

0.1 ± 1.4

14

Elderly

2.0 ± 1.2

2.1 ± 1.3

0.81 (0.53–0.93)

−0.1 ± 1.6

16

  1. Mean ± standard deviation (sd) for N2 latencies, N2P2 amplitudes, and cold ratings. Test–retest statistics are shown as intraclass correlation coefficients (ICC) with 95% confidence interval (CI) (“poor” < 0.40, “fair” = 0.41–0.60, “moderate” = 0.61–0.80, and “substantial” = 0.81–1.00) and Bland–Altman coefficients (test I–test II; mean ± 1.96 standard deviation (SD), limit of agreement) for all CEP parameters, stimulation sites (i.e., hand dorsum, hand palm, and foot dorsum), and age groups (i.e., young and elderly).
  2. N number of individuals, NRS numeric rating scale (0 = ‘not cold’ to 10 = ‘most imaginable cold’).