Figure 2 | Scientific Reports

Figure 2

From: Unusual clinical manifestations and predominant stopgain ATM gene variants in a single centre cohort of ataxia telangiectasia from North India

Figure 2

Representative image showing flow cytometric analysis of immunosenescent T lymphocytes in control (A) and patient (B). Elevated expression of CD57 marker revealed immunosenescence in the CD4+ (7.43% in comparison to the control 4.58%) and CD8+ T cells (29.30% in comparison to the control 8.43%). CD3+ T cells (constituting both CD4+ T helper and CD8+ T cytotoxic cells) were gated on CD3 vs SSc. Further, immunosenescence was estimated on the CD4+ and CD8+ cells.

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