Table 1 Length of telomeres (kb) in study subjects by the status of islet autoimmunity (IA) and type 1 diabetes (T1D) in the Environmental Determinants of Diabetes in the Young (TEDDY) study.
Parameter | Islet autoimmunity (IA) | Type 1 diabetes (T1D) | ||||
---|---|---|---|---|---|---|
Matched pairs n (%) | IA cases (in kb) | IA controls (in kb) | Matched pairs n (%) | T1D cases (in kb) | T1D controls (in kb) | |
Country | ||||||
Finland | 63 (16.20%) | 5.07 ± 0.76 | 5.22 ± 0.77 | 23 (19.49%) | 5.09 ± 0.78 | 5.02 ± 0.93 |
Germany | 13 (3.34%) | 5.13 ± 0.65 | 5.52 ± 1.08 | 5 (4.24%) | 5.39 ± 0.96 | 5.40 ± 0.27 |
Sweden | 182 (46.78%) | 5.13 ± 0.76 | 4.94 ± 0.84 | 49 (41.53%) | 5.22 ± 0.87 | 5.05 ± 1.05 |
U.S.A. | 131 (33.68%) | 5.24 ± 0.78 | 5.35 ± 0.84 | 41 (34.74%) | 5.16 ± 0.73 | 5.09 ± 0.84 |
Family history of T1D | ||||||
First-degree relative | 79 (20.31%) | 5.19 ± 0.64 | 5.19 ± 0.81 | 25 (21.19%) | 5.27 ± 0.84 | 5.07 ± 0.81 |
General population | 310 (79.69%) | 5.15 ± 0.79 | 5.13 ± 0.87 | 93 (78.81%) | 5.16 ± 0.80 | 5.07 ± 0.96 |
Sex | ||||||
Female | 169 (43.44%) | 5.23 ± 0.73 | 5.21 ± 0.88 | 52 (44.07%) | 5.28 ± 0.75 | 5.09 ± 0.96 |
Male | 220 (56.56%) | 5.10 ± 0.78 | 5.10 ± 0.84 | 66 (55.93%) | 5.10 ± 0.84 | 5.06 ± 0.91 |