Figure 4 | Scientific Reports

Figure 4

From: Mitochondrial dysregulation occurs early in ALS motor cortex with TDP-43 pathology and suggests maintaining NAD+ balance as a therapeutic strategy

Figure 4

CSMN that express mutated from of human TDP-43A315T extend shorter neurites in vitro. (a) representative images of CSMN from WT-UeGFP mouse; (b) representative images of CSMN from prpTDP-43A315T-UeGFP mouse model of ALS; (c) bar graph representation of average neurite length; (d) percent distribution of axon length; and (e) Sholl analysis of arborization of neurites. Scale bar = 20 µm.

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