Table 4 Mean residual ellipticity at 222 nm ([θ]222) and percent α-helical contents of LfcinB6, KR-12-a4 and Lf-KR in aqueous buffer, 50% TFE, 30 mM SDS and EYPC/EYPG (1:1) vesicles.

From: A novel hybrid peptide composed of LfcinB6 and KR-12-a4 with enhanced antimicrobial, anti-inflammatory and anti-biofilm activities

Peptide

Buffer

50% TFE

30 mM SDS

EYPC/EYPG (1:1)

[θ]222

% α-helix

[θ]222

% α-helix

[θ]222

% α-helix

[θ]222

% α-helix

LfcinB6

1446.6

rc

− 1073.2

rc

1071.2

rc

1405.1

rc

KR-12-a4

− 1619.9

rc

− 12,483.8

28.74

− 11,431.6

25.55

− 3430.0

rc

Lf-KR

− 1538.6

rc

− 10,967.4

24.14

− 10,534.3

22.83

− 7843.2

14.68

  1. % α-helix = − 100 ([θ]222 + 3000)/33,000.
  2. rc random coil.
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