Figure 2
2.5D model of a cell on a substrate exposed to capacitively coupled fields18. The 3D equivalent of the 2.5D model (zoomed-in) is shown in (a). The cell (red) adheres to a substrate (yellow) which is a plastic insulator with a thickness of \({1}\,\upmu \hbox {m}\). The cell has a radius of \({5}\,\upmu \hbox {m}\) and its membrane a thickness of \({5}\,\hbox {nm}\). The 2D view of the 2.5D model is shown in (b). On the top and bottom boundaries of the domain, Dirichlet boundary conditions are applied to impose a net voltage difference. The boundary conditions mimic the electrodes, which are not explicitly modelled. Note that the electrodes are not in direct contact with the medium since they are covered by insulators. The other boundaries are electrically insulating. Material parameters for the cell cytoplasm and the culture medium are assigned as stated in Table 1. Different locations along the curved part of the cell membrane are denoted by the angle with the symmetry axis. Positions along the bottom part are denoted by the distance to the cell centre.
