Figure 3

Dynamics of phosphosites in the ErbB pathway (the HER2-positive gastric cancer [pre-treatment] group versus the HER2-negative gastric cancer group). Proteins in the ErbB signaling pathway are selected from the KEGG database⁶⁵. Proteins with quantified phosphosites are shown as white boxes with solid lines. Proteins without quantified phosphosites are shown as grey boxes with dotted lines. Differentially expressed phosphosites with significance (log₂ |FC| > 1 and p < 0.05) are depicted by a purple line. Differentially expressed phosphosites with a tendency (log₂ |FC| > 1 and and 0.05 ≤ p < 0.1) are depicted by a green line.