Table 1 Demographic characteristics and systemic profiles of the subjects.

From: Evaluation of vascular endothelial growth factor (VEGF) level in the tears and serum of age-related macular degeneration patients

Variables

Total (n = 108)

Early AMD (n = 36)

Late AMD (n = 36)

Control (n = 36)

p value

Age (years)

(Mean ± SD)

64.3 ± 8.3

66.6 ± 7.1

68.7 ± 5.1

57.6 ± 8.1

< 0.001a

Sex (n, %)

Male

47 (43.5)

15 (41.7)

22 (61.1)

10 (27.8)

0.016b

Female

61 (56.5)

21 (58.3)

14 (38.9)

26 (72.2)

Race (n, %)

Malay

92 (85.2)

29 (80.6)

29 (80.6)

34 (94.4)

0.160b

Chinese

16 (14.8)

7 (19.4)

7 (19.4)

2 (5.6)

Lifestyle (n, %)

 Cigarette-smoking

  Active smoker

16 (14.8)

6 (16.7)

6 (16.7)

4 (11.1)

0.038b

  Ex-smoker

15 (13.9)

3 (8.3)

10 (27.8)

2 (5.6)

 Alcohol use history

  Social drinker

8 (7.4)

1 (2.8)

6 (16.7)

1 (2.8)

0.048c

Comorbidity (n, %)

Dyslipidemia

35 (32.4)

14 (38.9)

14 (38.9)

7 (19.4)

0.126b

Hypertension

57 (52.8)

19 (52.8)

22 (61.1)

16 (44.4)

0.367b

IHD

9 (8.4)

3 (8.3)

3 (8.3)

3 (8.3)

> 0.99c

DM

37 (34.3)

13 (36.1)

11 (30.6)

13 (36.1)

0.848b

CKD

8 (7.4)

7 (19.4)

1 (2.8)

0 (0)

0.005c

  1. AMD: age-related macular degeneration, IHD: ischemic heart disease, DM: diabetes mellitus, CKD: chronic kidney disease.
  2. aOne-way ANOVA.
  3. bChi-square test.
  4. cFisher’s exact test.