Figure 2

Phosphorus and platinum distributions in clinical samples using laser ablation ICP-MS (LA-ICP-MS). (A) Representative LA-ICP-MS images of high-grade serous ovarian cancer in primary debulking surgery as a negative control of the platinum and phosphorus and zinc distribution in tumor. Scale bar: 200 μm. (B) Images of phosphorus and platinum distributions in a clinically platinum-resistant recurrent ovarian tumor. Platinum was not present in the tumor but had accumulated in the borderline area of the tumor and stroma. Scale bar: 200 μm.