Table 2 Factors associated with death in the whole Italian series of people infected by SARS-CoV-2.

From: COVID-19 mortality in Italy varies by patient age, sex and pandemic wave

Feature

Hazard ratio (95% confidence interval)

P-value1

Age group (years)

0–14

0.12 (0.074–0.194)

 < 2 × 10–16

15–44

1.00

 

45–64

16.9 (15.5–18.4)

 < 2 × 10–16

65–74

126 (116–137)

 < 2 × 10–16

75–84

358 (328–390)

 < 2 × 10–16

 ≥ 85

691 (634–753)

 < 2 × 10–16

Sex

Female

1.00

 

Male

2.05 (2.03–2.08)

 < 2 × 10–16

Pandemic wave

Before June 30, 2020

1.00

 

From July 1 to December 31, 2020

0.379 (0.374–0.385)

 < 2 × 10–16

After December 31, 2020

0.346 (0.340–0.352)

 < 2 × 10–16

  1. Of the entire series, 108,316 cases were excluded due to incomplete or erroneous data, for a total of 4,224,698 SARS-CoV-2-positive subjects analyzed and 109,605 deaths within 30 days of diagnosis.
  2. 1Multivariable weighted Cox analysis (non-proportional hazards model).
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