Table 3 Factors associated with death in non-hospitalized subjects in the Italian national database.

From: COVID-19 mortality in Italy varies by patient age, sex and pandemic wave

Feature

Hazard ratio (95% confidence interval)

P-value1

Age group (years)

0–14

0.2959 (0.1443–0.6074)

9 × 10–4

15–44

1.000

 

45–64

16.19 (13.29–19.72)

 < 2 × 10–16

65–74

134.9 (111.2–163.7)

 < 2 × 10–16

75–84

527.7 (435.7–639.3)

 < 2 × 10–16

 ≥ 85

1457 (1203–1765)

 < 2 × 10–16

Sex

Female

1.000

 

Male

1.859 (1.813–1.904)

 < 2 × 10–16

Pandemic wave

Before June 30, 2020

1.000

 

From July 1 to December 31, 2020

0.3492 (0.3391–0.3602)

 < 2 × 10–16

After December 31, 2020

0.2112 (0.2041–0.2194)

 < 2 × 10–16

  1. Among non-hospitalized persons, 101,300 cases were excluded due to incomplete or erroneous data, for a total of 3,816,311 SARS-CoV-2-positive subjects analyzed and 27,409 deaths within 30 days of diagnosis.
  2. 1Multivariable weighted Cox analysis (non-proportional hazards model).