Figure 1
From: Sexual dimorphic impacts of systemic vincristine on lower urinary tract function
Comparison of changes in body weights, bladder weights and histology between VCR-administered and the control groups. (A) experimental timeline. (B) body weight was measured on the day before the first (−4wk) and fifth (−2wk) administration, the end of administration cycles (0wk) and 5 weeks after the last, 8th administration. (C) bladder weight measured at 5 weeks after the last administration of agents. Open and grey triangles indicate female mice in the control and VCR groups. Open and grey circles indicate male mice in the control and VCR groups [N = 12–15 per group per sex] Mean ± SE. **p < 0.005 vs. the control mice. Representative images of H&E staining (D) and collagen distribution (grey) in the bladder by SHG imaging (E). Scale bars = 400 µm. Figures were prepared using Adobe Photoshop CS6 and GraphPad Prism 8.4.3 (https://www.graphpad.com/scientific-software/prism/).
