Table 2 Comparison of urodynamic parameters between the groups.

From: Sexual dimorphic impacts of systemic vincristine on lower urinary tract function

Sex

Treatment [# animals]

Infused (µl)

Voided (µl)

Efficiency (%)

Pves max (cmH2O)

Compliance (µl/cmH2O)

NVCs (cycle−1)

F

Saline [4]

133 ± 9

131 ± 9

100 ± 3

20.5 ± 1.3

6.8 ± 0.4

0.1 ± 0.1

VCR [5]

168 ± 10*

167 ± 10*

100 ± 2

25.4 ± 0.9**

6.8 ± 0.5

0.8 ± 0.2**

M

Saline [6]

163 ± 12

162 ± 11

99 ± 2

22.8 ± 1.1

7.2 ± 0.3

0.5 ± 0.2

VCR [6]

246 ± 19**

248 ± 18**

102 ± 2

21.7 ± 1.0

11.3 ± 0.7**

1.4 ± 0.3*

  1. Significant increases in functional bladder capacity, voided volume, and the number of non-void contractions were observed in both female and male mice received VCR. VCR exposure induced increases in Pves max and bladder compliance in females and males, respectively, in comparison with the control group. Mean ± SE, *p < 0.05 and **p < 0.005 vs. the control group, Pves max, maximum intravesical pressure at micturition, NVCs, non-void contractions per micturition cycle.
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