Table 1 Patient characteristics at 6-month echocardiographic follow-up.
Variable | Non-HFrecEF (N = 227) | HfrecEF (N = 170) | P value | No. of patients analyzed |
|---|---|---|---|---|
Clinical characteristics | ||||
Age (years) | 74.6 ± 12.3 | 68.9 ± 13.6 | < 0.0001 | 397 |
Age ≥ 80 yearsa | 94 (41%) | 39 (23%) | < 0.0001 | 397 |
Womena | 74 (47%) | 63 (37%) | 0.36 | 397 |
BMI (kg/m2) | 22.8 ± 5.2 | 22.5 ± 4.3 | 0.63 | 299 |
BMI ≤ 22 kg/m2 | 85 (51%) | 67 (50%) | 0.89 | 299 |
Medical history | ||||
Atrial fibrillation or fluttera | 114 (50%) | 80 (47%) | 0.53 | 397 |
Hypertension | 167 (74%) | 105 (62%) | 0.01 | 397 |
Diabetes | 103 (45%) | 46 (27%) | 0.0002 | 397 |
Dyslipidemia | 112 (49%) | 51 (30%) | < 0.0001 | 397 |
Previous myocardial infarctiona | 85 (37%) | 24 (14%) | < 0.0001 | 397 |
Previous ischemic stroke or ICH | 33 (15%) | 15 (8.8%) | 0.08 | 397 |
Chronic lung disease | 32 (14%) | 14 (8.2%) | 0.07 | 397 |
Tests at 6-month visit | ||||
BNP (pg/mL) | 282.0 (141.1–587.9) | 83.5 (27.2–205.2) | < 0.0001 | 302 |
eGFR (mL/min/1.73m2) | 45.3 ± 19.9 | 52.2 ± 21.5 | 0.002 | 374 |
eGFR < 30 mL/min/1.73m2 a | 52 (24%) | 23 (15%) | 0.03 | 374 |
Albumin (g/dL) | 3.8 ± 0.5 | 4.1 ± 0.5 | < 0.0001 | 355 |
Albumin < 3 g/dL | 7 (3.4%) | 2 (1.3%) | 0.19 | 355 |
Hemoglobin (g/dL) | 12.3 ± 2.0 | 12.5 ± 2.5 | 0.40 | 370 |
Anemiaa | 126 (58%) | 75 (49%) | 0.09 | 370 |
Medications at 6-month visit | ||||
ACE-I or ARBa | 123 (65%) | 97 (69%) | 0.42 | 329 |
β-blockera | 153 (81%) | 127 (91%) | 0.007 | 328 |
MRAa | 89 (47%) | 75 (54%) | 0.26 | 328 |
Diuretics | 170 (90%) | 108 (77%) | 0.001 | 330 |
