Figure 2
From: Assessment of immunogenicity and drug activity in patient sera by flow-induced dispersion analysis
Overview and heatmap of 40 patient samples, showing the apparent hydrodynamic radius of TNF-α-AF488 (100 nM) as function of serum concentration (0–40% v/v) diluted with assay buffer, determined by FIDA at 25 °C (n = 3) with pre-incubated samples (> 10 min). Patients were renumbered and arranged according to response type. Last row depicts benchmark, based on values from a std. curve in 20% v/v plasma.
