Figure 3
From: Assessment of immunogenicity and drug activity in patient sera by flow-induced dispersion analysis
Experimental group (30 patients) depicted as lines with apparent hydrodynamic radius of TNF-α-AF488 (100 nM) as a function of serum concentration (0–40% v/v). The red dotted line shows theoretical benchmark values using the standard curve in 20% v/v plasma. The blue zone demonstrates 50% deviation in steady-state serum concentration of 8 µg/mL (~ 54 nM) adalimumab.
