Table 2 Change over time of BCVA (best corrected visual acuity), CMT (central macular thickness), FSRFT (foveal subretinal fluid thickness) and SFCT (sub foveal choroidal thickness) values in the SML group and the eplerenone group.

From: Short-term comparison between navigated subthreshold microsecond pulse laser and oral eplerenone for chronic central serous chorioretinopathy

Variable

Group

Baseline

30 days

60 days

90 days

p value

Groupa

Timeb

Interactionc

BCVA (logMAR)

SML

0.3 ± 0.1

0.1 ± 0.1

0.1 ± 0.1

0.1 ± 0.1

0.887

< 0.001

0.353

Eplerenone

0.3 ± 0.1

0.1 ± 0.1

0.1 ± 0.1

0.2 ± 0.1

CMT (μm)

SML

357.1 ± 104.3

250.2 ± 57.2

217.0 ± 31.3

210.6 ± 46.7

0.002

< 0.001

< 0.001

Eplerenone

428.7 ± 107.7

289.6 ± 77.3

267.7 ± 85.8

332.5 ± 27.5

FSRFT (μm)

SML

144.4 ± 108.2

56.3 ± 42.8

32.8 ± 26.4

22.6 ± 37.2

0.042

< 0.001

0.043

Eplerenone

217.1 ± 105.9

219.4 ± 108.9

95.0 ± 63.5

54.4 ± 86.2

SFCT (μm)

SML

383.2 ± 70.0

376.1 ± 45.4

354.4 ± 37.7

343.8 ± 49.1

0.184

0.083

0.071

Eplerenone

452.9 ± 127.9

386.9 ± 125.9

354.9 ± 94.3

387.4 ± 130.3

  1. Data are expressed as mean and standard deviation. Probability that effects of group on evaluated variables is influenced by:
  2. aGroups, for each variable, the differences has been tested between groups over times.
  3. bTime, for each variable, the differences have been tested between baseline, 30, 60 and 90 days of the two groups.
  4. cProbability that the effect of nutritional intervention is greater in one distinct group (interaction surgery*group).
  5. SML: subthreshold pulse laser.
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